Glasgow Medical Journal Volume 16 baixar o livro de graça

This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated.1881 Excerpt: ... FACET'S DISEASE OF THE NIPPLE. Bt ROBERT MUNRO, M.A., M.D., Kilmarnock. The clinical fact, first observed and announced by Sir James Paget, in 1874, of the frequency with which chronic eczema of the nipple was followed by mammary cancer, has since given rise to a very interesting discussion regarding the nature of the affection of the skin, and the pathological character of the breast-tumour subsequently developed. The enlargement of the area of observation by the publication of a considerable number of cases during the last few years has only strengthened the correctness of the original observation, but as to the incidental pathological questions or (what is of urgent practical importance) the diagnosis and treatment of the primary skin disease, unanimity has not yet been attained. At a meeting of the Royal Medical and Chirurgical Society, llth January, 1876, Mr. Butlin, F.R.C.S., read a paper "On the minute anatomy of two breasts, the areolae of which had been the seat of long standing eczema," in which he maintained, as the result of his histological observations, that the gland-ducts and acini were widely implicated in the morbid process as if by continuity from the cutaneous disease. The most significant pathological changes described consisted of distension and dilatation of the galoctophorous ducts and acini with proliferation of their epithelium. No actual cancer cells were, however, observed. About a year afterwards, 23rd January 1877, Mr. Butlin contributed another paper to the same Society " On the minute anatomy of two cases of carcinoma of the breast preceded by eczema of the nipple." The pathological conditions here described were precisely similar to the former; but in addition, "there were in these cases fusion of the acini and ducts thus fi...