Introduction to Cross-Coupling Reactions: Synthesis, Reactivity, and Practice baixar o livro de graça

This book provides an overview to and practice of cross-coupling reactions and their increasingly important role in organic synthesis. Each of the major cross-coupling reactions are covered - including Kumada, Negishi, Stille, Suzuki, Hiyama, Heck, Sonogashira, and Buchwald-Hartwig reactions. Chapters include synthesis and reactivity, literature references, mechanistic details, and example problems for the given reaction. Also featured in each chapter are practical aspects and a representative experimental procedure that illustrate the use of the reactions. A separate chapter covers lithiation chemistry, the most common route to prepare the organometallic reagents used in coupling reactions. The final chapter focuses on routinely-used catalysts, ligands, bases, and solvents in cross-coupling chemistry - very practical information needed by both students and professional bench chemists.